Murray’s Heroics Lift Cardinals Past Saints 20–13 in Tough Road Battle

Arizona Cardinals vs. New Orleans Saints — NFL 2025 Season Week 1 • Caesars Superdome

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The 2025 NFL season opened with a hard-fought NFC showdown at the Caesars Superdome as the Arizona Cardinals overcame the New Orleans Saints 20–13 in a contest defined by resilience, strategic adjustments, and a dramatic late-game finish. Quarterback Kyler Murray, battling illness, orchestrated the game-winning drive, while Arizona’s defense delivered clutch stops. The Saints, led by Spencer Rattler and Alvin Kamara, flashed promise but faltered against Arizona’s discipline.

Defense Dominates Early

The first quarter was a defensive standoff, with both teams trading punts. Early in the second, Jason Myers gave New Orleans a 3–0 lead with a 42-yard field goal. Arizona answered late in the half as Murray hit Michael Wilson for a 12-yard touchdown, pushing the Cardinals ahead 7–3. Despite illness, Murray remained composed, delivering accurate throws against New Orleans’ aggressive secondary.

Cardinals Adjust, Extend Lead

After halftime, Arizona leaned on high-percentage throws to offset the Saints’ pass rush. Rookie tight end Will Johnson snagged a 5-yard touchdown from Murray, making it 14–3. New Orleans countered with Kamara’s runs and Rattler’s mobility, but penalties and stalled third downs undermined progress.

Cardinals defense clamps Saints in second half
Arizona’s defense delivered timely stops and pressured Rattler throughout.

Defense Defines the Game

Linebacker Josh Sweat registered four pressures, forcing hurried throws. Rookie corner Will Johnson locked down deep options, contributing to an interception that set up prime field position. While the Saints’ front sacked Murray five times, missed tackles and red-zone lapses kept Arizona ahead.

Saints Rally Late

In the fourth, Rattler led a 10-play, 68-yard march capped by a 6-yard touchdown to Chris Olave, cutting it to 20–13. With momentum shifting, Arizona stayed calm. Murray converted two critical third downs, mixing short throws with Zach Charbonnet’s runs to drain the clock and secure the win.

Special Teams Impact

Kicker Eddy Pineiro was perfect, hitting both field goals. Myers scored all of New Orleans’ points (three FGs), but Arizona’s coverage units controlled field position late, limiting comeback chances.

Tactical Takeaways

The Saints opened with tempo and aggressive rush, but adjustments lagged. Arizona adapted with quick passes, clock management, and defensive rotations. Coaching fingerprints were clear: the Cardinals rotated personnel and emphasized matchups, while New Orleans failed to counter in crunch time.

Saints sideline urgency in tight game
Saints urgency grew as Arizona’s adjustments swung momentum.

Stat Leaders

  • Kyler Murray: 20/30, 245 YDS, 2 TD
  • Michael Wilson: 6 REC, 78 YDS, 1 TD
  • Will Johnson: 1 REC, 5 YDS, 1 TD
  • Spencer Rattler: 24/46, 198 YDS, 1 TD
  • Alvin Kamara: 15 carries, 62 YDS
  • Josh Sweat: 4 pressures, disruptive presence

Beyond the Numbers

Non-stat elements shaped the game: Murray’s poise despite illness, sideline communication, audibles, and motivational gestures. Crowd energy at the Superdome amplified intensity, especially during Arizona’s clock-killing drive.

Bottom line: Arizona’s 20–13 victory over New Orleans highlighted strategy, toughness, and individual brilliance. Murray’s resilience, supported by a disciplined defense, provided the blueprint. For New Orleans, the loss underscored red-zone lapses and execution gaps. Both teams leave Week 1 with lessons that will shape their seasons.